The global older adult population is expanding steadily, and falls represent a major geriatric health challenge associated with increased risks of disability and mortality. Although a substantial body of literature has examined risk factors for falls, findings vary across studies and populations. This review synthesizes evidence on fall-related risk factors in older adults and discusses implications for healthcare systems. Based on an integrated appraisal of the existing evidence, fall risk factors can be organized into three overarching domains: demographic factors (advanced age, female sex, educational attainment, race/ethnicity, and income), health-related factors (mobility, cognitive function, chronic conditions and multimorbidity, pharmacotherapy, frailty, psychological stress, history of falls, and falls self-efficacy), and environmental factors (rented accommodation, high door thresholds, slippery floors, and high-rise housing and other hazardous home environments). Notably, most falls occur in the home setting. The available literature also highlights an underassessment of psychological, sociodemographic, and environmental determinants of falls, thereby delineating priorities for future research. Given projections of continued population aging worldwide in the coming years, falls will impose a substantial burden on healthcare systems. Policymakers should therefore prioritize modifiable risk factors and implement targeted prevention strategies to reduce fall incidence among older adults.