A global perspective is one of the core competencies for contemporary graduate students in basic medical sciences, and an important objective in building a high-quality graduate education system. Guided by the "learning-centered" teaching philosophy, this study investigates and analyzes the knowledge needs and format preferences of students regarding global perspective training, using the compulsory graduate course "Pathogenesis" in basic medical sciences as the implementation platform to explore a training model for fostering a global outlook. Teaching practice demonstrates that the implementation of this model effectively expands the international academic perspective of students, with students reporting high satisfaction regarding course content and learning outcomes. This paper outlines the curriculum reform measures and application effects, proposes optimization suggestions for existing issues, and aims to provide a practical reference for cultivating a global perspective in graduate education.