Objective: To analyze the current status of Multidimensional Unithrust Inventory of Tinnitus (MUIS) scores in young and middle-aged patients with sudden sensorineural hearing loss complicated by tinnitus, and to identify the associated factors through multivariate linear regression analysis. Methods: A total of 100 middle-aged and young patients with sudden sensorineural hearing loss complicated by tinnitus, admitted to our hospital between January 2023 and December 2025, were selected. A retrospective study design was employed. Baseline data, including gender, age, duration of illness, history of smoking and alcohol consumption, daily routines, and psychological stress levels, were collected from the hospital’s electronic medical record system; Clinical data, including the degree of hearing loss and the affected ear, were collected; standardized scales were used to uniformly assess patients’ psychological state, sleep quality, and tinnitus distress. The MUIS scale was employed to evaluate the severity of tinnitus distress, and univariate analysis was conducted to identify factors influencing MUIS scores. Results: The patients’ MUIS scores averaged (48.62 ± 7.35) points, indicating moderate tinnitus discomfort. Univariate analysis revealed that age, duration of illness, degree of hearing loss, anxiety, depression, sleep quality, habit of staying up late, and psychological stress were factors influencing MUIS scores (P < 0.05); Multivariate linear regression analysis confirmed that severe hearing loss, a disease duration of ≥14 days, coexisting anxiety and depression, sleep disturbances, and chronic psychological stress were independent risk factors for elevated MUIS scores in young and middle-aged patients with sudden sensorineural hearing loss complicated by tinnitus (P < 0.05). Conclusion: The study indicates that patients with sudden sensorineural hearing loss and tinnitus in middle-aged and young adults generally experience more pronounced tinnitus-related discomfort, the severity of which is influenced by multiple factors, including hearing loss, duration of illness, psychological state, and sleep quality. Clinically, early screening and intervention targeting high-risk factors are necessary, with a focus on improving patients’ psychological state and sleep quality, precisely managing disease progression, and alleviating subjective tinnitus discomfort.