Objective: Investigation of the Diagnostic Value of Plain (Magnetic Resonance Imaging,MRI) and(Susceptibility Weighted Imaging,SWI) Sequences in Reperfusion Hemorrhage of Hemorrhagic Cerebral Infarction. Method: A total of 80 patients with suspected hemorrhagic cerebral infarction admitted to our hospital were enrolled as research subjects, with the enrollment period ranging from July 2023 to June 2025. All patients underwent plain magnetic resonance imaging (MRI) and susceptibility weighted imaging (SWI) sequence scans. Taking the clinical comprehensive diagnosis as the "gold standard", the diagnostic efficacies of plain MRI and SWI sequences were compared and analyzed. The Kappa consistency test was used to evaluate the consistency between the results of the two imaging methods and those of clinical comprehensive diagnosis. In addition, the differences in (Apparent diffusion coefficient ,ADC) values among patients with reperfusion hemorrhage of hemorrhagic cerebral infarction at different clinical stages (acute phase and subacute phase) within 24 hours after onset were compared. Results: Compared with plain magnetic resonance imaging (MRI), susceptibility weighted imaging (SWI) sequences showed significantly higher sensitivity, accuracy, and negative predictive value in the diagnosis of reperfusion hemorrhage in hemorrhagic cerebral infarction (all P < 0.05). The results of the consistency test indicated that plain MRI had poor consistency with the clinical comprehensive diagnosis (Kappa = 0.396, P = 0.003), whereas SWI sequences achieved moderate consistency with the clinical diagnosis (Kappa = 0.736, P = 0.000). The apparent diffusion coefficient (ADC) values of acute-phase patients at < 6 h, 6–< 12 h, and 12–24 h after onset were all lower than those of subacute-phase patients (all P < 0.05). Conclusion:Compared with plain MRI, SWI sequences have higher sensitivity, specificity, and accuracy in diagnosing reperfusion hemorrhage of hemorrhagic cerebral infarction. They can not only clearly identify the bleeding status but also evaluate the disease progression after onset through changes in ADC values, thereby providing a reliable reference for clinicians to formulate diagnosis and treatment plans and possessing high clinical promotion value.