瘢痕子宫再次妊娠产妇行产钳助产并发产后出血的风险评分简表建立及其有效性验证
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丰城市人民医院

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宜春市科技计划项目(编号:JXYC2024KSA267);


Development and Validation of a Risk Scoring Tool for Postpartum Hemorrhage in Women with Scarred Uteri Undergoing Forceps-Assisted Delivery#
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    摘要:

    目的:建立瘢痕子宫再次妊娠产妇行产钳助产并发产后出血的风险评分简表,并验证其诊断价值。方法:前瞻性选取2024年1月到2024年12月于我院就诊的瘢痕子宫再次妊娠并行产钳助产的产妇120例作为研究对象,并且依据患产妇是否并发产后出血进行分组:出血组47例;未出血组73例;单因素分析影响瘢痕子宫再次妊娠产妇行产钳助产并发产后出血的风险因素,采用多因素logistic回归分析影响瘢痕子宫再次妊娠产妇行产钳助产并发产后出血的独立风险因素并构建评分简表,绘制ROC曲线来分析其诊断价值。结果:出血和未出血两组产妇年龄、孕前身体质量指数(Body Mass Index,BMI)、孕次、分娩孕周、子宫瘢痕厚度、两次妊娠间隔时间、人工流产刮宫史、子宫手术史、新生儿体质量、妊娠期高血压、妊娠期糖尿病、胎盘早剥、胎盘黏连/植入、软产道损伤情况以及产前(纤维蛋白原(Fibrinogen,Fbg)、活化部分凝血活酶时间(Activated Partial Thromboplastin Time,APTT)、国际标准化比值(International Normalized Ratio,INR)、凝血酶原时间(Prothrombin Time,PT)、血红蛋白(Hemoglobin,Hb))水平对比,差异存在统计学意义(P<0.05)。 将单因素分析筛选出因素进行多因素Logistic回归分析结果显示,新生儿体质量、妊娠期高血压、妊娠期糖尿病、胎盘早剥、胎盘黏连/植入、软产道损伤情况以及产前(Fbg、Hb)水平均是瘢痕子宫再次妊娠产妇行产钳助产并发产后出血的独立影响因素(P<0.05)并将其纳入快速评估简表。ROC曲线分析结果显示,评分简表预测瘢痕子宫再次妊娠产妇行产钳助产并发产后出血的AUC为0.862(95%CI:0.775~0.948,P<0.05)。结论:本研究构建的瘢痕子宫再次妊娠产妇行产钳助产并发产后出血的风险评分简表,经ROC曲线分析验证具有良好的预测效能,因此该简表可作为临床评估工具来有效识别高危产妇并为预防产后出血提供重要参考。

    Abstract:

    Objective: To develop and validate a concise risk scoring tool for predicting postpartum hemorrhage (PPH) in women with scarred uteri undergoing forceps-assisted delivery in a subsequent pregnancy.Methods: A total of 120 women with a scarred uterus who were again pregnant, delivered at our hospital between January and December 2024, and underwent forceps-assisted delivery were prospectively enrolled as the study population. Participants were divided into two groups based on the occurrence of PPH: 47 in the hemorrhage group and 73 in the non-hemorrhage group. Univariate analysis was used to identify potential risk factors. Multivariate logistic regression was then applied to determine independent predictors of PPH and to construct a simplified risk scoring tool. The diagnostic performance of the tool was evaluated using ROC curve analysis.Results:Significant between-group differences (P < 0.05) were observed in maternal age, pre-pregnancy BMI, gravidity, gestational age at delivery, uterine scar thickness, inter-pregnancy interval, history of curettage or uterine surgery, neonatal birth weight, gestational hypertension, gestational diabetes, placental abruption, placenta accreta/increta, soft birth canal injury, and prenatal levels of fibrinogen (Fbg), activated partial thromboplastin time (APTT), international normalized ratio (INR), prothrombin time (PT), and hemoglobin (Hb). Multivariate logistic regression identified neonatal birth weight, gestational hypertension, gestational diabetes, placental abruption, placenta accreta/increta, soft birth canal injury, and prenatal Fbg and Hb levels as independent predictors of PPH (P < 0.05). These variables were incorporated into a rapid assessment scoring tool. ROC analysis yielded an AUC of 0.862 (95 % CI: 0.775–0.948, P < 0.05), indicating good predictive accuracy.Conclusion: The newly developed risk scoring tool demonstrates strong predictive performance for PPH in women with scarred uteri undergoing forceps-assisted delivery. It can serve as an effective clinical instrument to identify high-risk parturients and guide preventive strategies against postpartum hemorrhage.

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曾文娟.瘢痕子宫再次妊娠产妇行产钳助产并发产后出血的风险评分简表建立及其有效性验证[J].四川生理科学杂志,2026,48(2):

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  • 收稿日期:2025-10-28
  • 最后修改日期:2025-11-12
  • 录用日期:2025-11-28
  • 在线发布日期: 2026-02-24
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