Objective: To explore the clinical effect of phlegm-heat patch combined with Western medicine in the treatment of pediatric pneumonia. Methods: A total of 92 children who were willing to participate in the study were selected from the pediatric pneumonia patients admitted to our hospital. From January to December 2024, the grouping method for enrolled children was coin toss. Among them, 46 children in the control group received treatment with amoxicillin and clavulanate potassium, and 46 children who received combined treatment with phlegm heat patches were included in the study group. After one week of treatment, the treatment effect and clinical symptom scores of the two groups were compared, the lung function indexes were detected by pulmonary function tester, the levels of inflammatory factors were measured by automatic biochemical analyzer and automatic blood routine analyzer, and the incidence of adverse drug reactions was compared. Results: Statistical analysis showed that the number of patients in the study group who met the criteria for significant and limited efficacy was higher than that in the control group, and the difference between the groups was significant (P<0.05); After treatment, the clinical symptom scores of both groups of children decreased compared to before, with the study group showing a greater degree of change and being lower than the control group (P<0.05); After treatment, the levels of various inflammatory factors in both groups of children were detected and compared. Both groups showed a decrease compared to before, with the study group showing a greater decrease, which was lower than the control group (P<0.05); There was no significant difference in the occurrence of adverse drug reactions between the two groups of children (P>0.05). Conclusion: In the treatment of pediatric pneumonia with amoxicillin and clavulanate potassium, the application of phlegm heat patches can effectively alleviate clinical symptoms, eliminate inflammation, and promote the recovery of lung function. The therapeutic effect is safe and significant, and it has positive significance for promoting the recovery of children"s conditions.