Objective: To explore the correlation between echocardiographic right ventricular function parameters and prognosis in patients with chronic obstructive pulmonary disease (COPD) and pulmonary hypertension (PH). Methods: A total of 60 patients with COPD and PH in the hospital were retrospectively enrolled between March 2020 and March 2024. According to short-term curative effect, they were divided into effective group (n=39) and ineffective group (n=21). The right ventricular function parameters [diameter of main pulmonary artery in short axial segment of main artery (MPA), (right ventricular free wall thickness (RVWT), basal transverse diameter of right ventricle (RVd1), middle transverse diameter of right ventricle (RVd2), left-right diameter of right atrium (RAd), tricuspid annular plane systolic excursion (TAPSE)], serum NT-proBNP and lung function [forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC, 6-minute walking distance (6MWD)] were compared between the two groups. The correlation between each index and short-term curative effect was evaluated by Spearman analysis, and predictive value of each index was analyzed by multivariate Logistic regression analysis and ROC curves. Results: MPA, RVWT and NT-proBNP in effective group were lower than those in ineffective group, while TAPSE was higher than that in ineffective group (P<0.05). MPA, RVWT and serum NT-proBNP were negatively correlated with the curative effect (P<0.05), while TAPSE was positively correlated with it (P<0.05). MPA, RVWT and NT-proBNP were risk factors of curative effect, while TAPSE was a protective factor. The area under the curve (AUC) values of MPA, RVWT, TAPSE and NT-proBNP for predicting curative effect in patients with COPD abd PH were 0.783, 0.773, 0.795 and 0.760, respectively. AUC of combined detection was 0.850, greater than that of single index. Conclusion: Echocardiographic right ventricular function parameters (MPA, RVWT, TAPSE) and NT-proBNP are of evaluation value for curative effect in patients with COPD and PH.