新生化片联合芬吗通预防人工流产术后宫腔粘连的有效性及安全性
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景德镇市妇幼保健院

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景德镇市科技计划项目(编号:景科字[2024]37号);


Effectiveness and Safety of Xinshenghua Tablets Combined with Femoston on Preventing Intrauterine Adhesions after Artificial Abortion#
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    摘要:

    目的:探讨新生化片联合芬吗通预防人工流产术后宫腔粘连(IUA)的有效性及安全性。方法:收集2025年1月至2025年6月于本院行人工流产终止早期妊娠的患者70例,根据给药方案分为A组(n=35,给予芬吗通),B组(n=35,给予新生化片联合芬吗通)。比较两组患者的IUA发生率、月经恢复情况、子宫内膜厚度、血流参数[阻力指数(RI)、搏动指数(PI)]及不良反应发生率。结果:术后1个月,A组的IUA发生率高于B组,且B组月经恢复情况优于A组(P<0.05)。治疗后,2组子宫内膜厚度变厚,RI、PI降低,且B组子宫内膜厚度厚于A组,RI、PI低于A组(P<0.05)。两组不良反应发生率,无显著差异(P>0.05)。结论:新生化片联合芬吗通可有效降低人工流产术后IUA发生率,促进术后子宫内膜修复、月经恢复,安全性良好。

    Abstract:

    Objective: To explore the effectiveness and safety of Xinshenghua tablets combined with femoston on the prevention of intrauterine adhesions (IUA) after artificial abortion. Methods: 70 patients who underwent artificial abortion to terminate early pregnancy in the hospital from January 2025 to June 2025 were collected and divided into group A (n=35, femoston) and group B (n=35, Xinshenghua tablets combined with femoston) according to the dosage regimen. The incidence rate of IUA, menstrual recovery conditions, endometrial thickness, blood flow parameters [resistance index (RI), pulsatility index (PI)] and incidence rates of adverse reactions were compared between groups. Results: At 1 month after surgery, the incidence rate of IUA in group A was higher than that in group B, and the menstrual recovery conditions in group B were better than those in group A (P<0.05). After treatment, the endometrial thickness in the two groups was thickened, and the RI and PI were decreased, and the endometrial thickness in group B was thicker, and the RI and PI were lower than those in group A (P<0.05). There were no obvious differences in the incidence rates of adverse reactions between groups (P>0.05). Conclusion: Xinshenghua tablets combined with femoston can effectively reduce the incidence rate of IUA after artificial abortion, and promote the postoperative endometrial repair and menstrual recovery, with good safety.

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邹雅洲.新生化片联合芬吗通预防人工流产术后宫腔粘连的有效性及安全性[J].四川生理科学杂志,2026,48(2):

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  • 收稿日期:2025-08-18
  • 最后修改日期:2025-09-08
  • 录用日期:2025-09-18
  • 在线发布日期: 2026-02-24
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