Objective: To compare the diagnostic efficacy of digital radiography (DR) mammography and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for non-calcified breast invasive ductal carcinoma (IDC), providing a basis for optimizing clinical diagnostic pathways. Methods: 62 patients with suspected breast IDC admitted between January 2023 and January 2025 were enrolled. All patients underwent both DR and DCE-MRI examinations. Using postoperative pathological results as the gold standard, the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and area under the receiver operating characteristic curve (AUC) of the two methods were evaluated. Results: The detection rates of spiculated masses, architectural distortion, and axillary lymph node metastasis by DCE-MRI (89.3%, 62.5%, 32.1%) were all higher than those by DR mammography (60.7%, 28.6%, 14.3%), with statistically significant differences (P<0.05). The sensitivity, NPV, and AUC of DCE-MRI (96.4%, 71.4%, 0.94) were all higher than those of DR mammography (75.0%, 22.2%, 0.78), with statistically significant differences (P<0.05). In the group with lesion maximum diameter ≤ 2 cm, the sensitivity of DCE-MRI (92.3%) was higher than that of DR mammography (57.7%), with a statistically significant difference (P<0.05). Conclusion: DCE-MRI demonstrates superior diagnostic sensitivity and higher detection rate for small lesions compared to DR mammography in non-calcified breast IDC. DCE-MRI is recommended as a supplementary modality to DR mammography.