硬膜外分娩镇痛中局麻药浓度与产间发热程度及持续时间的相关性分析
DOI:
作者:
作者单位:

赣州市南康区妇幼保健院

作者简介:

通讯作者:

中图分类号:

基金项目:

赣州市指导性科技计划项目(编号:GZ2024ZSF447);


Correlation analysis of local anesthetic concentration in epidural labor analgesia with intrapartum fever degree and duration#
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
    摘要:

    目的:分析硬膜外分娩镇痛中局麻药浓度与产间发热程度及持续时间的相关性。方法:回顾性分析本院2024年1月~2024年12月期间66例接受硬膜外分娩镇痛镇痛产妇临床资料,按局麻药浓度分为高浓罗哌卡因组(0.15%)和低浓度罗哌卡因组(0.075%),两组各33例。比较两组产妇的发热程度、持续时间、疼痛情况(VAS)、分娩结局及舒适度调查表(GCS)得分、产间血清炎性因子水平,并分析产间发热程度及持续时间与局麻药浓度相关性。结果:罗哌卡因浓度越高,孕妇发热程度明显更高,发热持续时间明显更长,VAS评分明显更低,自然分娩率更低,阴道协助分娩率更高,GCS评分明显更低,胎儿分娩1小时后的IL-6、TNF-α、CRP水平越高,且组间存在统计学意义(P<0.05);局麻药浓度与发热程度、发热持续时间存在显著的正相关关系(P<0.05)。结论:硬膜外分娩镇痛中局麻药浓度与发热程度、发热持续时间呈正相关,使用低浓度罗哌卡因有助于获得较高舒适度,促进自然分娩,但高浓度罗哌卡因能更有助于预防撤去疼痛泵后的疼痛。

    Abstract:

    Objective: To analyze the correlation between local anesthetic concentration in epidural labor analgesia and degree and duration of intrapartum fever. Methods:? The clinical data of 66 parturients undergoing epidural labor analgesia in the hospital from January 2024 to December 2024 were retrospectively analyzed. According to the local anesthetic concentration, they were divided into high-concentration ropivacaine group (0.15%) and low-concentration ropivacaine group (0.075%), with 33 cases in each group. The fever degree, duration, pain status (VAS), delivery outcomes, comfort questionnaire (GCS) score and the level of serum inflammatory factors were compared between the two groups, and the correlation between intrapartum fever degree and duration and local anesthetic concentration was analyzed. Results: The higher the concentration of ropivacaine was, the pregnant women significantly higher the degree of fever was, the significantly longer the duration of fever was, the significantly lower the VAS score was, the lower the natural delivery rate was, the higher the vaginal assisted delivery rate was, the lower the GCS score was, the higher the levels of IL-6, TNF-α and CRP after 1 hour of fetal delivery was(P<0.05). There was a significant positive correlation between local anesthetic concentration and fever degree and fever duration (P<0.05). Conclusion: The local anesthetic concentration in epidural labor analgesia is positively correlated with fever degree and fever duration. The application of low-concentration ropivacaine is helpful to obtain high comfort and promote natural delivery, but high-concentration ropivacaine can be more helpful to prevent pain after withdrawal of pain pump.

    参考文献
    相似文献
    引证文献
引用本文

阳宇婷.硬膜外分娩镇痛中局麻药浓度与产间发热程度及持续时间的相关性分析[J].四川生理科学杂志,2025,47(9):

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2025-06-04
  • 最后修改日期:2025-07-15
  • 录用日期:2025-07-23
  • 在线发布日期: 2025-09-24
  • 出版日期: