Abstract:Objective: To analyze the correlation between local anesthetic concentration in epidural labor analgesia and degree and duration of intrapartum fever. Methods:? The clinical data of 66 parturients undergoing epidural labor analgesia in the hospital from January 2024 to December 2024 were retrospectively analyzed. According to the local anesthetic concentration, they were divided into high-concentration ropivacaine group (0.15%) and low-concentration ropivacaine group (0.075%), with 33 cases in each group. The fever degree, duration, pain status (VAS), delivery outcomes, comfort questionnaire (GCS) score and the level of serum inflammatory factors were compared between the two groups, and the correlation between intrapartum fever degree and duration and local anesthetic concentration was analyzed. Results: The higher the concentration of ropivacaine was, the pregnant women significantly higher the degree of fever was, the significantly longer the duration of fever was, the significantly lower the VAS score was, the lower the natural delivery rate was, the higher the vaginal assisted delivery rate was, the lower the GCS score was, the higher the levels of IL-6, TNF-α and CRP after 1 hour of fetal delivery was(P<0.05). There was a significant positive correlation between local anesthetic concentration and fever degree and fever duration (P<0.05). Conclusion: The local anesthetic concentration in epidural labor analgesia is positively correlated with fever degree and fever duration. The application of low-concentration ropivacaine is helpful to obtain high comfort and promote natural delivery, but high-concentration ropivacaine can be more helpful to prevent pain after withdrawal of pain pump.