Objective: To analyze the diagnostic value of multimodal magnetic resonance imaging (MRI) for cerebral venous sinus thrombosis. Method: A retrospective analysis was conducted to collect clinical data of 62 patients with cerebral venous sinus thrombosis admitted to Suiping County People"s Hospital from January 2022 to December 2024. All patients received multimodal MRI after admission, and the diagnostic value of multimodal MRI for the number and distribution of thrombus involved segments in patients with cerebral venous sinus thrombosis was analyzed. Result: A total of 810 venous sinus segments were identified in 62 patients with cerebral venous sinus thrombosis, including 678 normal segments and 132 segments affected by thrombosis. Thrombosis involving segments above the sagittal sinus was more common, accounting for 36.36%. The accuracy, specificity, and sensitivity of multimodal MRI in diagnosing the number of segments involved in cerebral venous sinus thrombosis in patients were 97.28%, 98.82%, and 89.39%, respectively. The overall accuracy of multimodal MRI in diagnosing the distribution of thrombus involvement segments in patients with cerebral venous sinus thrombosis was 91.67%, with the accuracy, specificity, and sensitivity of the superior sagittal sinus being 99.24%, 100.00%, and 97.92%, respectively. The accuracy, specificity, and sensitivity of the sigmoid sinus were 96.97%, 97.92%, and 94.44%, respectively. The accuracy, specificity, and sensitivity of the transverse sinus were 92.42%, 95.19%, and 82.14%, respectively. The diagnostic accuracy, specificity, and sensitivity of the straight sinus were 95.45%, 97.32%, and 85.00% (17/20), respectively. The diagnostic results of multimodal MRI for the number and distribution of thrombus involved segments in patients with cerebral venous sinus thrombosis were consistent with the results of DSA examination (Kappa ≥ 0.75, P<0.001). Conclusion: Multi mode MRI has high diagnostic value for cerebral venous sinus thrombosis and can assist in clinical clarification of the number and distribution of thrombus involved segments.