孕晚期超声血流参数对妊娠期高血压疾病孕妇母婴结局的预测价值
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于都县妇幼保健院

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赣州市指导性科技计划项目(编号:GZ2024ZSF479);


Predictive value of ultrasound blood flow parameters in late pregnancy on maternal-infant outcomes in pregnant women with gestational hypertension#
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    摘要:

    目的:探究孕晚期超声血流参数对妊娠期高血压疾病孕妇母婴结局的预测价值。方法: 纳入2023年1月到2024年12月收治62例的孕晚期妊娠期高血压疾病孕妇作为研究对象,采用彩色多普勒测定血流参数。根据分娩结局分为分娩正常组(n=46)与分娩异常组(n=16)。对比2组超声血流参数,采用二元logistics方程分析患者发生不良分娩结局相关影响因素;采用ROC曲线分析超声血流参数对不良分娩结局的预测价值。根据围生儿结局分为围生儿结局正常组(n=52)与围生儿结局异常组(n=10),对比2组超声血流参数,采用二元logistics方程分析患者发生不良围生儿结局相关影响因素;采用ROC曲线分析超声血流参数对不良围生儿结局的预测价值。结果:分娩异常组与围生儿结局异常组脐动脉、子宫动脉PI、RI、S/D均分别高于分娩正常组与围生儿结局正常组(P<0.05),而大脑中动脉PI、RI、S/D均显著低于分娩正常组与围生儿结局正常组(P<0.05);脐动脉、子宫动脉以及大脑中动脉PI、RI、S/D与妊娠期高血压疾病患者发生不良分娩结局及不良围生儿结局相关(P<0.05);以脐动脉、子宫动脉及大脑中动脉PI、RI、S/D为检验变量,ROC曲线结果显示,其预测妊娠期高血压疾病患者发生不良分娩结局与不良围生儿结局的AUC分别为0.730、0.832、0.836、0.719、0.700、0.755、0.798、0.836、0.719与0.706、0.979、0.921、0.910、0.737、0.775、0.900、0.913、0.9925。结论:孕晚期超声血流参数可有效预测妊娠期高血压疾病不良孕妇母婴结局,具有临床价值。

    Abstract:

    Objective: To explore the predictive value of ultrasound blood flow parameters in late pregnancy on maternal-infant outcomes in pregnant women with gestational hypertension. Methods: 62 pregnant women with late pregnancy hypertension admitted from December 2023 to December 2024 were included as the study subjects, and blood flow parameters were measured using color Doppler. According to the delivery outcome, they were divided into a normal delivery group (n=40) and an abnormal delivery group (n=22). Compare two sets of ultrasound blood flow parameters and use binary logistics equations to analyze the factors related to adverse delivery outcomes in patients; Using ROC curve analysis to evaluate the predictive value of ultrasound blood flow parameters for adverse delivery outcomes. According to the perinatal outcomes, patients were divided into a normal perinatal outcome group (n=46) and an abnormal perinatal outcome group (n=16). The ultrasound blood flow parameters of the two groups were compared, and binary logistics equations were used to analyze the factors related to adverse perinatal outcomes in patients; Using ROC curve analysis to evaluate the predictive value of ultrasound blood flow parameters for adverse perinatal outcomes. Results: The PI, RI, S/D of the umbilical artery and uterine artery in the abnormal delivery group and the abnormal perinatal outcome group were higher than those in the normal delivery group and the normal perinatal outcome group, respectively (P<0.05), while the PI, RI, and S/D of the middle cerebral artery were significantly higher than those in the normal delivery group and the normal perinatal outcome group (P<0.05); The PI, RI, S/D of umbilical artery, uterine artery, and middle cerebral artery are associated with adverse delivery outcomes and adverse perinatal outcomes in patients with gestational hypertension (P<0.05); Using PI, RI, S/D of the umbilical artery, uterine artery, and middle cerebral artery as test variables, the ROC curve results showed that the AUC for predicting adverse delivery outcomes and adverse perinatal outcomes in patients with pre pregnancy hypertension were 0.730, 0.832, 0.836, 0.719, 0.700, 0.755, 0.798, 0.836, 0.719 and 0.706, 0.979, 0.921, 0.910, 0.737, 0.775, 0.900, 0.913, 0.992 respectively. Conclusion: Ultrasound blood flow parameters in late pregnancy can effectively predict maternal and infant outcomes in pregnant women with gestational hypertension, and have clinical value.

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邹玉娟.孕晚期超声血流参数对妊娠期高血压疾病孕妇母婴结局的预测价值[J].四川生理科学杂志,2025,47(9):

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  • 收稿日期:2025-05-09
  • 最后修改日期:2025-07-22
  • 录用日期:2025-08-01
  • 在线发布日期: 2025-09-24
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