Objective: To investigate the predictive efficiency of blood glucose variability parameters on recent cardiovascular events in patients with coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM). Methods: A total of 120 patients with CHD and T2DM in the hospital from November 2022 to August 2024 were selected as subjects of this study. According to the presence or absence of recent cardiovascular events, 120 patients were divided into non-occurrence group (no recent cardiovascular events, n=96) and occurrence group (recent cardiovascular events, n=24). The general data, fasting plasma glucose (FPG), glycosylated hemoglobin (HbA1c), blood glucose variability parameters [standard deviation of blood glucose (SDBG), mean amplitude of glycemic excursions (MAGE), fasting plasma glucose coefficient of variation (FPG-CV), largest amplitude of glycemic excursions (LAGE)] were compared between the two groups. The predictive efficiency of blood glucose variability parameters on recent cardiovascular events was analyzed by receiver operating characteristic (ROC) curve. Results: The body mass index (BMI), FPG, HbA1c, SDBG, MAGE, FPG-CV and LAGE at admission in occurrence group were higher than those in the non-occurrence group (P<0.05). ROC curve showed that the AUCs of BMI, FPG, HbA1c, SDBG, MAGE, FPG-CV and LAGE in predicting recent cardiovascular events in CHD patients with T2DM were 0.756, 0.719, 0.785, 0.884, 0.828, 0.923 and 0.880, and the sensitivities were 66.67%, 70.83%, 72.83%, 83.33%, 87.50%, 79.17% and 75.00%, and the specificities were 84.37%, 69.79%, 81.25%, 84.37%, 72.92%, 90.62% and 89.58% respectively. Compared with BMI, FPG and HbA1c, the predictive efficiency of blood glucose variability parameters was higher (P<0.05). Conclusion: The occurrence of recent cardiovascular events in CHD patients with T2DM is closely related to the increases of blood glucose variability parameters. Monitoring the blood glucose variability parameters of patients is helpful to predict the occurrence of recent cardiovascular events in CHD patients with T2DM.