Objective: Explore the impact of continuous improvement in neonatal resuscitation quality combined with management of non-nutritional sucking position on the prognosis of premature infants.Methods:The postoperative blood pressure (PaO2) and oxygen saturation (SaO2) of newborns were significantly higher than those in the control group, but the carbon dioxide blood pressure (PaCO2) was significantly lower than that in the control group (p<0.05). The Apgar score of the observation group was significantly higher than that of the control group (p<0.05). The recovery time of birth weight, gastric retention time and total intestinal feeding time in the control group were shorter than those in the control group (p<0.05). The incidence of complications in the follow-up group was significantly lower than that in the control group (p<0.05).Results:Blood oxygen partial pressure (PaO2) and arterial oxygen saturation (SaO2) in the postoperative neonatal observation group were significantly higher than in the control group, but arterial carbon dioxide partial pressure (PaO2) was significantly lower than in the control group (P<0.05). The Apgar score in the observation group was significantly higher than in the control group (P<0.05). The recovery time of birth weight, gastric tube retention time and total enteral feeding time in the observation group were shorter than in the control group, and the data difference was statistically significant (P<0.05). The incidence of complications in the observation group was significantly shorter than in the control group (P<0.05).Conclusion:The intervention method to continuously improve the quality of neonatal resuscitation combined with the non-nutritional sucking position can significantly improve blood gas indicators and Apgar scores of premature infants, shorten weight recovery at birth, gastric tube retention and the entire intestinal feeding cycle, reduce the incidence of complications and shorten hospitalization times. Therefore, this method of intervention is worthy of clinical promotion and application.