基于超声评估下的体外膈肌刺激疗法对慢阻肺急性加重期患者肺功能、膈肌功能及撤机时机的影响
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郑州大学第一附属医院综合重症监护病区

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    目的:基于超声评估下的体外膈肌刺激疗法对慢阻肺急性加重期患者肺功能、膈肌功能及撤机时机的影响。方法:选取我科2022年10月至2024年6月期间106例慢阻肺急性加重期患者为研究对象,依照随机数表法分组。对照组53例给予常规治疗,观察组53例另给予基于超声评估下的体外膈肌刺激疗法,对比两组肺功能、膈肌功能及撤机时机。结果:治疗后,两组最大通气量、第1秒用力呼气末容积、用力肺活量比值、第1秒用力呼气末容积与用力肺活量比值均升高,且观察组更高(P<0.05)。治疗后,两组呼气末膈肌厚度、吸气末膈肌厚度、膈肌增厚分数、膈肌活动度均升高,且观察组更高(P<0.05)。治疗后,观察组撤机时间和平均住院时间均短于对照组(P<0.05)。结论:基于超声评估下的体外膈肌刺激疗法用于慢阻肺急性加重期患者能够改善肺功能和膈肌功能,并且可以缩短撤机时间。

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    Objective: To evaluate the effects of external diaphragm stimulation therapy based on ultrasound on pulmonary function, diaphragm function and withdrawal time in patients with COPD acute exacerbation. Methods: 106 patients with acute exacerbation of COPD in our department from October 2022 to June 2024 were selected as the study objects and grouped according to random number table method. The control group (53 cases) received conventional treatment, and the observation group (53 cases) received external diaphragm stimulation therapy based on ultrasound evaluation. The pulmonary function, diaphragm function and withdrawal time of the two groups were compared. Results: After treatment, the maximum volume, forced expiratory volume in the first second, forced vital capacity ratio, forced expiratory volume in the first second to forced vital capacity ratio were increased in the two groups, and the observation group was higher (P<0.05). After treatment, the end expiratory diaphragm thickness, end inspiratory diaphragm thickness, diaphragm thickening fraction and diaphragmatic activity were increased in both groups, and were higher in the observation group (P<0.05). After treatment, the withdrawal time and average hospitalization time of the observation group were shorter than those of the control group (P<0.05). Conclusion: Extracorporeal diaphragm stimulation based on ultrasound evaluation can improve lung function and diaphragm function in patients with COPD acute exacerbation, and can shorten the withdrawal time.
    Keywords:Ultrasound; External diaphragm stimulation therapy; Copd; Lung function; Diaphragm function

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曹青杨.基于超声评估下的体外膈肌刺激疗法对慢阻肺急性加重期患者肺功能、膈肌功能及撤机时机的影响[J].四川生理科学杂志,2025,47(8):

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  • 收稿日期:2024-09-25
  • 最后修改日期:2024-11-05
  • 录用日期:2024-11-08
  • 在线发布日期: 2025-08-31
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