Objective: To observe the effect of orthodontic treatment with micro-implants in patients with Anschian class II type 1 malocclusion. Method: Eighty patients with malocclusion who were diagnosed and treated in our hospital from October 2022 to October 2023 were selected as the research subjects. The patients were divided into the control group and the observation group by random number method, with 40 cases in each group. The control group was treated with traditional external oral arch orthodontics, while the observation group was treated with micro-implant orthodontics. The orthodontic effects [the Angle between the long axis (U1) of the upper central incisor and the SN plane (anterior cranial base plane) (U1-SN Angle); The intersection Angle of the long axis (L1) of the lower central incisors and the mandibular plane (MP) (L1-MP Angle)], masticatory Function [Chewing Function Questionnaire (CFQ)] and the occurrence of complications of the two groups were analyzed and compared. Result: After 18 months of treatment, the U1-SN angles of both groups were significantly reduced compared with those before treatment, but the L1-MP angles of both groups showed no significant changes compared with those before treatment. Moreover, the U1-SN Angle of the observation group after 18 months of treatment was significantly smaller than that of the control group (P < 0.05). However, there was no significant difference in the L1-MP Angle between the two groups (P > 0.05). After 18 months of treatment, the CFQ scores of both groups were significantly higher than those before treatment, and the CFQ score of the observation group was significantly higher than that of the control group (P < 0.05). The incidence of postoperative complications in the observation group was lower than that in the control group (P < 0.05). Conclusion: The use of micro-implant orthodontics for Anshi Class II type 1 malocclusion can improve orthodontic effects, promote the recovery of masticatory function, and reduce postoperative complications.