Objective: To explore the influencing factors of ptosis in cataract patients after Phacoemulsification (PHCAO) combined with Intraocular Lens Implantation (ILI). Methods: The clinical data of 126 cataract patients diagnosed with phacoemulsification combined with intraocular lens implantation in our hospital from March 2021 to March 2024 were retrospectively collected. According to the occurrence of ptosis after phacoemulsification combined with intraocular lens implantation, the patients were divided into the occurrence group and the non-occurrence group. Baseline data were collected and compared. Logistic regression analysis was performed to determine the influencing factors of ptosis in cataract patients after PHCAO combined with ILI. Results: Among 126 cataract patients treated by phacoemulsification combined with intraocular lens implantation, 34 cases (26.98%) had ptosis and were included in the occurrence group. 92 patients without ptosis were included in the group without ptosis. There were significant differences in age ≥60 years old, metabolic syndrome, periocular anesthesia, and the proportion of eyelid opening used in the occurrence group compared with the non-occurrence group (P < 0.05). Logistic regression analysis showed that age, metabolic syndrome, anesthesia method, and intraoperative use of eyelid open were all risk factors for ptosis after PHCAO and ILI in cataract patients (P < 0.05). Conclusion: The incidence of ptosis is higher in cataract patients treated by phacoemulsification combined with intraocular lens implantation. Among them, the age of patients, metabolic syndrome, anesthesia method, and the use of eyelid opening during the operation are all factors that affect the ptosis of cataract patients after PHCAO combined with ILI.